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POINT OF VIEW AT THE PROBLEM OF ATRIAL FIBRILLATION IN OBESE PATIENTS

Popov Vladimir Viktorovich  (Doctor of Medical Sciences, Professor, Head of the Department of Family Medicine and Internal Medicine of the Federal State Budget Educational Institution of Higher Education “Northern State Medical University” of the Ministry of Healthcare of the Russian Federation (Arkhangelsk city).)

Ryabaya Irina Nikolaevna  (Candidate of Medical Sciences, Associate Professor of the Department of Family Medicine and Internal Medicine of the Federal State Budget Educational Institution of Higher Education “Northern State Medical University” of the Ministry of Healthcare of the Russian Federation (Arkhangelsk city).)

Kalaida Maria Konstantinovna  (Assistant of the Department of Family Medicine and Internal Medicine of the Federal State Budget Educational Institution of Higher Education “Northern State Medical University” of the Ministry of Healthcare of the Russian Federation (Arkhangelsk city).)

Atrial fibrillation (AF) has a negative impact not only on the quality of life of patients, but also leads to cardioembolic complications, which increases mortality and disability of the population. Currently, studies show that the presence of obesity has a significant impact on the occurrence and recurrence of AF. In recent years, studies have been carried out proving the negative effect of adipose tissue on the myocardium, which manifests itself in changes in the structure of the myocardium and its functional state. Adipose tissue is a secretory organ capable of producing biologically active substances-adipokines that affect the processes of cardiac remodeling and is capable of supporting the processes of chronic inflammation; the most significant inflammatory activity is observed in epicardial adipose tissue. A practicing physician needs knowledge of the mechanisms of development and features of the manifestation of AF in patients with obesity in order to improve patient management tactics taking into account the principles of personalized medicine.

Keywords:atrial fibrillation, obesity, leptin, adiponectin, resistin, paroxysms, epicardial adipose tissue

 

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Citation link:
Popov V. V., Ryabaya I. N., Kalaida M. K. POINT OF VIEW AT THE PROBLEM OF ATRIAL FIBRILLATION IN OBESE PATIENTS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№02. -С. 179-183 DOI 10.37882/2223-2966.2024.02.29
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