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Personalized medicine in pain management

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E. Golubenko, E. Silina, A. Orlova  (I.M. Sechenov First Moscow State Medical University of the Russian Ministry of Health)


Series «Natural & Technical Sciences», № 07-08  2017


The effectiveness and specificity of modern analgesics are insufficient. Studies of genetic polymorphisms associated with pain syndromes and the metabolism of drugs foreshadow a new therapeutic approach with targeted analgesia and fewer side effects. The purpose of this work is to assess the association of the patient's genetic profile and its response to perception, the onset of pain and the therapeutic response to analgesics.

Keywords: pain syndrome, targeted analgesia, genetic profile, pain pharmacogenetics, opioid analgesics, antiepileptic drugs, cyclic antidepressants.

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© E. Golubenko, E. Silina, A. Orlova,  Journal "Modern Science: actual problems of theory and practice".
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