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Cell-potentiated technologies with stromal vascular fraction application in plastic surgery of the face

Karpiuk Vladimir Borisovich  (candidate of medical sciences, Stavropol state medical university)

Lavreschin Petr Mikhaylovich  (doctor of medical sciences, professor, Stavropol state medical university)

Gayvoronskaya Tatiana Vladimirovna  (doctor of medical sciences, professor, Kuban state medical university (Krasnodar))

To assess the opportunities of cell-potentiated surgical techniques, which include autologous stromal-vascular fraction (SVF) transplanta-tion, treatment outcomes in 203 patients with local soft tissue deficiency of the face and 24 patients with defects and deformations of the facial skeleton were studied. It is determined that SVF-enriched fat tissue trans-plantation (control group, n=105) is safe. In comparison with traditional technique of lipofilling (main group, n=98) it is characterized by high effi-ciency one-time correction (2,0±0,1 and 1,4±0,1 GAIS scores, groups re-spectively, p≤0,01), a decrease in multiplicity of interventions to achieve optimal results in the most difficult clinical cases (1,7±0,1 and 2,1±0,1 operations on the one patient, groups respectively, p≤0.01). Reconstruc-tive surgery of the facial skeleton, including the implantation of SVF-enriched biodegradable osteoplastic materials demonstrate high efficiency in patients with saddle nose deformity (dynamics of the FACE-Q scores: satisfaction with nose 41,4±3.2 and 74,6±2,6 (p<0.001); psychological function 46.6±4,6 and 79.5±2,9 (p<0.001); social function 45.5±2.3 and 69,8±3,3 (p<0,001) before and after surgery respectively), congenital cleft of the upper jaw, post-traumatic chin deformation, orbital floor defect, combined dentoalveolar and facial anomalies.

Keywords:Cell-potentiated technologies, stromal vascular fraction, lipofilling, maxil-lo facial reconstruction.
 

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Citation link:
Karpiuk V. B., Lavreschin P. M., Gayvoronskaya T. V. Cell-potentiated technologies with stromal vascular fraction application in plastic surgery of the face // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2017. -№06. -С. 94-98
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