Performance of indicators of hemostasis in optimization of infusion and transfusion therapy with mass bleeding

Saidov Jurakhon Safolovich, Qubiddinov Azmiddin Fayzulloevich, Odinaev Aziz Abdusattorovich, Homidov Jura Butaevish, Belyh Vladimir Ivanovich

The article deals with investigation showing that hemorrhage of category 1 is followed by moderate changes of homeostasis activation of platelet and coagulation, fibrinolysis relief with adaptive character and is referred to stop the bleeding. Infusion crystalloids in required volumes compensate the loss of blood quite adequately. However, capacity of 9% sodium chlorides to develop metabolic acidosis makes injurious effect on the system of homeostasis. A number of its parameters differs from control rate even in a week after occurrence of incident. Regarded in this light, Strefundin isotonic solution has certain preference, which provides normalization of homeostasis in 3 days after hospitalization without affecting on internal environment of the organism.

Keywords:ulcerative homeostasis; homeostasis, criteria of treatment; conservative therapy