Peculiarities of remodeling of the cardiovascular system in pregnant women with arterial hypertension

Fridman Tatiana Mikhailovna, Torsunova Yulia Petrovna, Pastukhov Alexander Dmitrievich

Remodeling of the cardiovascular system is one of the important morphological and functional changes that determine the damage to target organs in arterial hypertension. Since in the course of pregnancy arterial hypertension may develop in several ways, it is interesting to follow the peculiarity of the transformation of the heart and blood vessels, depending on the etiology of high blood pressure. The analysis of the features of the transformation of the heart and blood vessels during and after pregnancy was carried out in 102 women with arterial hypertension of different etiology. The main methods were used to measure blood pressure, daily blood pressure monitoring, and also echocardiography was performed, assessing cardiac remodeling according to A. Ganau's classification (1992). During the examination in the third trimester of pregnancy, the majority of patients with chronic arterial hypertension showed pathological cardiac remodeling, similar changes were recorded in almost a third of pregnant women with gestational arterial hypertension and in half of the patients with pre-eclampsia. After childbirth, positive changes in the structure of the heart and blood vessels were observed in all three groups, however, in most women with chronic arterial hypertension, signs of remodeling persisted. The maximum positive dynamics in the transformation of the heart and blood vessels was observed among patients with gestational arterial hypertension.

Keywords:remodeling, arterial hypertension, pregnancy, preeclampsia, cardiovascular system