Diagnostic significance of biomarkers of the inflammatory processes of respiratory tract

Imetova Zhazgul Bukarbayevna, Kalmatov Romanbek Kalmatovich, Abdurakhmanov Baktyar Omurbekovich

Review and analysis of literature data on the possibilities of using biological markers for the timely diagnosis of pathology of the lungs and respiratory tract indicates the discovery of a number of new molecules involved in the pathogenesis of local manifestations of diseases of the upper respiratory tract. Non-invasive methods for studying the composition of exhaled air condensate are widely used as methods for the clinical evaluation of inflammation and oxidative stress in the distal respiratory tract for respiratory diseases. This approach allows to detect early changes at the molecular level with the defeat of various departments of the respiratory system, which in turn makes it possible to scientifically substantiate the prognostic criteria of the inflammation risk, occupational and production-related diseases of the respiratory system, and also provides opportunities for the development and improvement of efficient methods of diagnosis and therapy.

Keywords:respiratory tract, bronchial asthma, exhaled breath condensate, oxidative stress, biomarkers