Cognitive disorders in patients with liver cirrhosis: association with intestinal microflora

Ataeva Abidat Akhmalutdinovna, Molchanov Nikolay Sergeevich

The development of hepatic encephalopathy (HE) in patients with liver cirrhosis (LC) is a very topical issue, as it occurs in more than 30% of patients and significantly reduces their quality of life. The mechanisms for the development of PE in CP are still not fully understood, but lately there has been increasing evidence of the role of the intestinal microbiota in the development of cognitive impairment. In this paper, we have tried to highlight the main work published on this issue today, but further research in this direction is very relevant, since a clear understanding of the pathogenesis of cognitive disorders in liver cirrhosis and the role of intestinal microbiota in these processes will allow us to develop new approaches in the treatment of these patients that will undoubtedly improve their quality of life.

Keywords:hepatic encephalopathy, liver cirrhosis, cognitive impairment, intestinal microbiota, intestinal microflora.