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Leading microbial pathogens of urinary infections in the department of body transplantation and opportunities for optimization of therapy

Ruina O. V.  (Candidate of Medical Sciences, Associate Professor, Privolzhskiy Research Medical University, N. Novgorod)

Stroganov A. B.  (Doctor of Medical Sciences, Associate professor, Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, N. Novgorod)

Konishkina T. M.  (Candidate of Medical Sciences, Associate Professor, Privolzhskiy Research Medical University, N. Novgorod)

Osmanov A. M.  (Clinical resident of Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, N. Novgorod)

Kurushin A. M.  (Clinical resident of Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, N. Novgorod)

Dudukina Y. A.  (Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, N. Novgorod)

Kozlova E. A.  (Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, N. Novgorod)

Zaitceva E. I.  (Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, N. Novgorod)

Тhe microbial pathogens from the urine of patients from the organ transplantation department of a high-tech hospital in 2017 – 2018 was studied. 42 etiologically significant strains were found. Gram-negative pathogens (57%) were found to be the leading microbial pathogens of the urinary tract in the organ transplantation department. Most often the Enterobacteriaceae was found. The prevalence of Klebsiella pneumoniae was revealed (up to 24%), the level of beta-lactamase production in these pathogens was 72%, and carbapenem-resistant strains were also found. Thus, it is possible to predict the inefficiency of standard antimicrobial therapy prescribed in the recommendations for the treatment of urinary tract infections.

Keywords:kidney transplantation, microbes, resistance, antibiotic therapy

 

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Citation link:
Ruina O. V., Stroganov A. B., Konishkina T. M., Osmanov A. M., Kurushin A. M., Dudukina Y. A., Kozlova E. A., Zaitceva E. I. Leading microbial pathogens of urinary infections in the department of body transplantation and opportunities for optimization of therapy // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2019. -№11. -С. 189-192
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