C-reactive protein as atrial fibrillation risk factor

Redka Andrey Victorovich, Chernych Tatiana Mihailovna

Atrial fibrillation (AF) accounts for 30% of all rhythm disturbances. It is known that nervous and endocrine systems change their properties due to myocardium electrical instability. Certain data indicate that immune system factors can be the cause of cardiac rhythm disturbance. In order to search information the authors used such data bases as Pubmed, eLibrary, dissercat. Retrieval requests were atrial fibrillation and C-reactive protein (CRP), atrial fibrillation and inflammation. C-reactive protein (CRP) can be considered a sensitive laboratory marker of tissue inflamma-tion and damage. It is strongly related to IL-6 plasma level. IL-6 as a proinflammatory cytokine plays the key role in activation and maintenance of inflammation.

Keywords:atrial fibrillation, inflammation, autoimmune inflammation, cytokines.