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The relationship between allelic variants of serotonergic system genes and anxiety level among studens

Gumerova O. V.  (Candidate of Sciences in Biology, docent, Bashkirian State Pedagogical University named after M. Akmulla (Ufa))

Davydova Yu. D.  (graduate student, Institute of Biochemistry and Genetics, Ufa Science Centre of RAS (Ufa))

Galikeeva G. F.  (Candidate of Sciences in Biology, docent, Bashkirian State Pedagogical University named after M. Akmulla (Ufa))

The analysis of the relationship between allelic variants of serotonergic system genes involved in biosynthesis (TPH1, TPH2), transport (SLC6A4), receptions (HTR1A, HTR1B, HTR2A, HTR2C, HTR3A) and degradation (MAO-A) of serotonin and anxiety level among students was held. The statistical analysis showed significant differences in the distribution of allelic variants TPH1, TPH2, HTR3A genes and revealed a four-factor model of the interaction of the TPH1, TPH2, HTR2A and HTR3A genes, which determine high and low indices of anxiety.

Keywords:anxiety, behavior, serotonin, serotonergic system, students.
 

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Citation link:
Gumerova O. V., Davydova Y. D., Galikeeva G. F. The relationship between allelic variants of serotonergic system genes and anxiety level among studens // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2020. -№08. -С. 16-19 DOI 10.37882/2223-2966.2020.08.10
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