Severity of intestinal microbiota disorders depending on the age of the patient gastroenterological hospital patients

Esaulova Tatyana Alekseevna, Kochina Irina Igorevna, Bazaeva Olga Viktorovna, Zyazina Elena Nikolaevna

this Work is devoted to the study of intestinal microbiota in various age groups in a gastroenterological hospital. The aim of the study is to determine the severity of violations of the microbiota of the large intestine, depending on age. The method of the study was a retrospective analysis of medical records of patients ' medical histories of the gastroenterological Department of the Astrakhan state hospital No. 3 from 2009-2019. As a result of the study, it was found that the most pronounced changes in the intestinal microbiota are characteristic of the age over 60 years, the least pronounced-for patients aged 40 to 60 years, patients aged 20 to 40 years in terms of the severity of dysbiosis occupy an intermediate position. This may be due to the fact that the formation of chronic diseases of the gastrointestinal tract at a young age begins to occur maladaptive processes in the intestinal microbiota, which may decrease under the influence of various factors, including treatment, normalization of the immune response, which we saw in the 1 and 2 age groups. However, if the damage to the digestive system persists for a long period, the severity of changes in the intestinal microbiota increases as much as possible.

Keywords:intestinal microbiota, dysbiosis, normal microflora, conditionally pathogenic microflora, aerobic bacteria, pathogenic microflora.