Clinical relevance of ambulatore for predicting the development of preeclampsia in overweight pregnant women with hyperandrogenism

Manukhina Е. I., Sakvarelidze N. Yu., Ispas A. A.

This paper presents the results of the examination of 70 overweight female patients with hyperandrogenism. Those women got pregnant after a complex post-syndrome treatment with metabolic correction. When performing ambulatory blood pressure monitoring inpatient session, certain similar patterns of blood pressure fluctuations were found. Patients had blood pressure fluctuations, a two-phase rhythm “day-night”, and morning and evening blood pressure peak. During the daytime, systolic pressure was 140,2+/-2,1 mm Hg, diastolic pressure was 89,0+\-2,1 mm Hg. In the night, systolic pressure was 136,5+/-2,8 mm Hg, diastolic pressure was 84+\-6,3 mm Hg. The average value of pulse pressure in patients was 53 mm Hg, the range of pulse pressure fluctuations among women in this group was 21-57 mm Hg. In obstetric practice, ambulatory blood pressure monitoring has a high diagnostic value.

Keywords:hyperandrogenism, obesity, ambulatory blood pressure monitoring, preeclampsia, antihypertensive therapy.