Pathophysiological aspects and hemodynamic renal disorders in nephropathy associated with antiphospholipid syndrome

Albakova Maddan, Albakova Hadizhet, Bogatyreva Lidiya, Gagieva Dolatkhan

The article is devoted to the problem of kidney pathology in adults and children with nephropathy associated with antiphospholipid syndrome (APS). Nephropathy is part of the clinical picture of APS. Thrombotic microangiopathy (TMA), which is a special type of vascular lesion in the microvasculature of various organs, is the cornerstone of nephropathy in APS. APS-nephropathy (APSN) is a predictively unfavorable independent disease. The clinical picture of APS-associated nephropathy is characterized by a variety of severity of clinical symptoms. The main symptoms of APS-nephropathy, which form the clinical variants of APSN, are described. The differences in the course of APS-associated nephropathy among men, women and children are shown.

Keywords:antiphospholipid syndrome (APS), vascular disorders, kidneys.