Method for determining the sensitivity of a chemotherapy drug to breast cancer

Ramazanov Mutalim Ramazanovich, Abdurakhmanova Zagidat Mutaelumovna

Aim. Development of a new method for determining the sensitivity of a chemotherapy drug to breast cancer, which is available for republican oncological medical institutions. Materials and methods of research. The study included 175 patients with breast cancer (T2-3N1-2 M0). The main group included 86 patients, and the comparison group – 89. The developed method for determining the sensitivity of a chemotherapy drug to breast cancer consists in the fact that the material taken from the tumor is treated with a chemotherapy drug for 2 hours, stained with trepan blue and the presence or absence of malignant cells on a slide determines the sensitivity of the chemotherapy drug to breast cancer. Results. After the use of the developed method in the clinic, 86 patients of the main group with breast cancer did not have relapses and metastases. In the comparison group, in 89 patients who did not use the new method for determining the sensitivity of a chemotherapy drug to breast cancer, breast cancer recurrences were found in 9 patients and metastases in 4. Conclusions 1. A method for determining the sensitivity of a chemotherapy drug to breast cancer was developed and used in the clinic in 86 patients. 2. Clinical trials have shown that a new method for determining the sensitivity of a chemotherapy drug to breast cancer improves the results of breast cancer chemotherapy.

Keywords:breast cancer, sensitivity of a chemotherapy drug to breast cancer.