Application hemostatic agents. possibilities and prospects of sodium alginate and chitosan

Shvetsov Ivan Sergeevich

The presented review systematizes the current literature data on the most relevant issues of applied hemostatic agents: definition, classification, range of active components and biomaterials, the mechanism of achieving hemostasis, restrictions in use, requirements for local hemostatics and methodological approaches to confirm hemostatic activity. The existing interdisciplinary research aimed at the development and study of local hemostatic agents allows us to focus on the possibilities and prospects of using sodium alginate and chitosan as a biomaterial, as well as to identify the main trends in the development of means for achieving local hemostasis. One such trend is a group of local hemostatics based on combinations of sodium alginate, carboxymethylchitosan and active components.

Keywords:hemostasis, application hemostatic agents, local hemostatics, local bleeding, sodium alginate, chitosan, carboxymethylchitosan