Features of the oral microbiota of patients with chronic generalized periodontis in residents of the Tversky region

Chervinets Vyacheslav Mikhailovich, Chervinets Yulia Vyacheslavovna, Leont᾽eva Aurelia Valerievna, Belyaev Vsevolod Stanislavovich, Stulov Nikita Mikhailovich, Rodionov Andrey Alexandrovich, Chervinets Alina Vyacheslavovna, Troshin Andrey Valerievich, Rumyantsev Vitalij Anatol'evich

it was analized the spectrum, frequency of occurrence and the number of oral microbiota of the residents of the Tver region: healthy and patients with chronic generalized periodontitis of moderate severity in the period of remission were analyzed. Material was collected and analyzed from 4 biotopes: dental plaque, scraping from the mucous membrane of the dorsum of the tongue, oral fluid and the contents of the gingival groove or the contents of the periodontal pocket. In all biotopes, classical periodontopathogens were not identified, but the appearance of Streptococcus agalactiae was noted in 40-65% of cases (p = 0.003) in the amount of 3-7.5 lg CFU / ml (p = 0.024). Dysbiotic changes were not revealed in the content of dental plaque. In scraping from the tongue, in most cases, representatives of the commensal microbiota, Lactobacillus spp. and Peptоstrеptоcossus spp. Streptocossus spp. were found in the parodontal pocket. and Peptostreptocossus spp. in 80% of cases, Streptococcus agalactiae - in 45%, Peptocossus spp. - 40%. In the oral fluid of people with periodontitis, an increase in the incidence of representatives of Bacillus spp. was noted almost in 13 times.

Keywords:chronic generalized periodontitis, microbiota, oral cavity, dysbiosis.