First-time diagnosed atrial fibrillation and obesity in elderly people in therapeutic practice

Ryabaya Irina Nikolaevna, Serdechnaya Elena Valerievna, Yurieva Svetlana Vladimirovna

The reduction of death and cardiovascular events in patients with atrial fibrillation (AF) and obesity remains an urgent problem. A study involving 220 patients with AF and arterial hypertension (AH) was conducted on the basis of the SBOU VO "SSMU" of the Ministry of Health of the Russian Federation, Arkhangelsk. Inclusion criteria: The first diagnosed form of AF, the presence of arterial hypertension in the anamnesis and at the time of inclusion. The aim of the study was to identify the features of AF in overweight and obese patients. The body mass index (BMI) was calculated, the concentration of leptin in the blood was determined, ECHO-KG, repeated paroxysms of AF were recorded by performing an ECG. The study showed that in patients with AF in the obese groups, the size of the left ventricle, the left atrium, the frequency of left ventricular hypertrophy is higher than in the group with normal body weight. An increase in body weight is associated with an increase in the frequency of repeated paroxysms of AF. The concentration of leptin was significantly higher in the group of patients with repeated paroxysms. Conclusions: Obesity contributes to the progression of myocardial remodeling and an increase in repeated paroxysms of AF. The concentration of leptin is higher in the blood in patients with repeated paroxysms of AF.

Keywords:atrial fibrillation, structural indicators of the cardiovascular system, obesity, paroxysm, leptin.