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Is there a place for radiation therapy in the treatment of locally advanced ovarian cancer

Sharabura Tatyana Mikhailovna  (Ph.D., State Medical Institution "St. Petersburg Clinical Research and Practice Center for Specialized Types of Medical Care (Oncological)")

Moiseyenko Vladimir Mikhailovich  (Doctor of Medical Sciences, Professor, Director, St. Petersburg Clinical Research and Practice Center for Specialized Types of Medical Care (Oncological)")

Khadzhimba Anzhella Slavikovna  (Doctor of Medical Sciences, St. Petersburg Clinical Research and Practice Center for Specialized Types of Medical Care (Oncological)»)

Scherbatykh Darya Evgenievna  (Researcher, St. Petersburg Scientific and Clinical Center for Specialized Types of Medical Care (Oncology))

The generally accepted standard treatment for epithelial ovarian cancer is currently performing optimal cytoreductive surgery with adjuvant chemotherapy with platinum and taxanes. Primary treatment ensures complete clinical remission in more than 70%, but most patients with a locally advanced process experience a relapse of the disease, mainly with intra-abdominal localization. Adjuvant radiation therapy with pelvic abdominal radiation used in the 1950s was inferior to platinum-containing chemotherapy in efficacy and toxicity and was excluded from recommendations for the treatment of ovarian cancer. Modern technologies of radiation therapy make it possible to take a fresh look at the capabilities of the method both for consolidating remission after first-line therapy and for treating relapses of the disease.

Keywords:ovarian cancer, radiation therapy, treatment

 

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Citation link:
Sharabura T. M., Moiseyenko V. M., Khadzhimba A. S., Scherbatykh D. E. Is there a place for radiation therapy in the treatment of locally advanced ovarian cancer // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2021. -№04. -С. 235-240 DOI 10.37882/2223-2966.2021.04.38
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