Influence of vitamin D deficiency on the cardiovascular system

Vengrzhinovskaya Oksana Igorevna, Bondarenko Irina Ziyatovna

vitamin D deficiency is diagnosed in about 30-50% of the world's population [1]. It should be noted that Vitamin D deficiency increases in proportion to the distance from the equator, which explains the increased filtration of UV rays. [2]. It causes not only chit, osteoporosis, osteomalacia, but also cardiovascular pathology. The Russian and foreign studies presented in this review prove that moderate and severe vitamin D deficiency is a risk factor for the development of cardiovascular diseases. [3]. A decrease in the level of vitamin D in humans is a risk factor for cardiovascular pathology: arterial hypertension (AH), diabetes mellitus (DM), dyslipidemia, myocardial fibrosis and a predictor of adverse cardiovascular events - strokes and heart attacks. It has been shown that vitamin D has a protective effect on blood vessels, reducing endothelial dysfunction, has a positive effect on blood pressure, slows down vascular remodeling and myocardial fibrosis, reduces the risk of left ventricular hypertrophy and atherosclerosis, reduces insulin resistance, and affects the course of inflammatory processes [4].

Keywords:vitamin D deficiency, 25(ОН)D, 1,25(OH)2D, сardiology, arterial hypertension, atherosclerosis, disturbance of heart rate, congestive heart failure.