Homocysteine level in patients with complicated and uncomplicated course of acute coronary syndrome against the background of undifferentiated connective tissue dysplasia syndrome

Sultanova Oksana Esedullayevna, Chernysheva Elena Nikolaevna, Kiseleva Maria Alekseevna, Kuzmichev Bogdan Yurevich

To study the level of homocysteine (HC) in acute coronary syndrome (ACS) against the background of undifferentiated connective tissue dysplasia (UCTD), we examined 241 patients aged 35 to 65 years who were on inpatient treatment in the State Medical Institution of JSC Kirov State Clinical Hospital No. 3 and in the RSC AM Clinical Hospital. It was revealed that in patients with ACS on the background of UCTD, there is a statistically significant increase in the level of HC in blood plasma - 38.4 mmol/l, compared with the control group and with patients with ACS without UCTD. The highest level of HC was registered in patients with complicated ACS on the background of SNDST - 41.5 mmol/l. It was found that in patients with ACS and UCTD, the increased content of HC was 4 times more common than in people without somatic pathology and was statistically significantly higher (p <0.001).

Keywords:acute coronary syndrome, undifferentiated connective tissue dysplasia, homocysteine.