Peculiarities of the influence of environmental factors on the humoral immunity indicators of human body

Zakharov Nikita Evgenevich, Kondrashova Irina Nikolaevna, Kondykova Nataliia Nikolaevna

The paper presents the results of studies of the content of immunoglobulins of different classes in the saliva of qualified athletes aged 19-22 living in ecologically different areas. The concentration of immunoglobulins is one of the most important characteristics of the state of humoral immunity. The impact of environmental factors on the state of humoral immunity and the immunological status of the organism has been assessed. Immunoglobulin concentrations were determined by one-dimensional radial immunodiffusion. A decrease in the concentration of immunoglobulins in the saliva of athletes under the influence of intensive physical activity against the background of adverse environmental factors of radiation and chemical nature was revealed. There is a significantly lower concentration of immunoglobulin A in the saliva of athletes from adverse environmental areas compared to clean areas. Changes in immunity corresponding to the first stage of changes in the immunological parameters, when immunodeficiency states do not arise yet, but the risk of developing immunodeficiency is quite high are noted against the background of the combined effect of the adverse environmental factors and high athletes’ physical activity.

Keywords:environmental factors, immune status, immunoglobulins, humoral immunity, athletes.