The influence of genetically determined alimentary-constitutional obesity on the state of the cardiovascular system: literature review

Avdeev Igor Viktorovich

The article discusses the relationship of obesity and cardiovascular pathology. The risk of developing cardiovascular diseases directly depends on the presence of obesity and overweight in the patient. The main prospects of the study are associated with the study of the influence of genetic and molecular genetic factors for the development of obesity. In some studies, it is indicated for a significant role of genetic factors in the development of obesity and for the presence of a close relationship of genetically determined obesity with cardiovascular pathology. Genetically determined alimentary-constitutional obesity is a separate obesity form, which causes complex biochemical and metabolic violations, leads to the development of numerous complications. It is practically not amenable to treatment, therefore, paramount importance should be given to prevention. Violations of the normal state of the SCCs can manifest themselves both structural and functional changes. As obesity progressing, these disorders are transformed into heart failure. Hemodynamic violations caused by obesity as the main trigger. Most often we are talking about hypercoagulation, increasing peripheral vascular resistance. This is accompanied by an increase in cardiac output, and according to an increase in the mass of myocardium.

Keywords:cardiovascular pathology, obesity, alimentary-constitutional obesity, genetic factors, hypercoagulation.