Proliferative activity of dermal fibroblasts depending on the concentration of carbon dots

Golderova Aitalina Semenovna, Shadrina Svetlana Semyonovna, Nikolaeva Irina Eduardovna, Egorova Marfa Nikitichna, Evseeva Yulia Ruslanovna, Troev Ivan Petrovich, Егоров Андрей Николаевич

The article describes an experimental study on human dermal fibroblast cells. The aim of the study was to evaluate in vitro the proliferative activity of human dermal fibroblasts depending on the concentration of carbon dots (CD). By the end of the experiment, the most "affected" was the group to which the largest volume of carbon dots solution (50 ml) was added, the group with the smallest volume (10 ml) was practically not "affected". The results obtained confirm that the toxicity of UT depends on the protocol of their manufacture and is detected only at higher concentrations.

Keywords:carbon dots, fibroblasts, cytotoxicity, cell culture, proliferation, hydrothermal method, bird cherry, positive charge, concentration, in vitro.