The potential role of the disorders of the human gut microbiota as an initial link in the pathogenesis of diseases of the immune system, and of diseases associated with neuroinflammation

Eremenko Ivan Ivanovich

The investigation of various aspects of pathogenesis of immune diseases (for example, reactions of hypersensibility and different types of allergy) lead to understanding the fact of participation of gut microbiota at the modulation of normal functioning of the immune system. There are new arguments for the role of maternal immune activation (MIA) in the pathogenesis of nervous and psychical disorders of the children, and also the medical scientists explore the role of the gut microflora at forming the neuroinflammation and it’s possible participation at the pathogenesis of neurodegenerative disorders. However, there are a lot of new questions and argues and very little amount of answers. The review of last results in the problem of connection between gut microbiota and immune system have a purpose of critical assessment of it and the popularization of one of the most perspective trends in the immunopathology

Keywords:allergy, immunopathology, microbiota, maternal immune activation, neuroinflammation