Clinical characteristics and outcomes of SARS-CoV‑2 (COVID‑19) patients with myocardial infarction

Prokhorov K. V., Koriagina N. A., Spasenkov G. N., Koriagin V. S., Avdeev A. V.

There is limited information available on the clinical characteristics and outcomes of SARS-CoV-2 (COVID-19) patients with myocardial infarction. Materials and methods. In our one-center retrospective study, we reviewed 28 patients admitted to the vascular center from October 01, 2020 to November 30, 2020. A total of 28 19 (67.8%) of whom were men, with an average age of 65 [58, 71] years and a high burden of comorbidities. Results. During hospitalization, 14 (50%) developed acute respiratory distress syndrome, and 8 (28%) required mechanical ventilation. 23 (82%) patients received primary percutaneous coronary intervention (PCI), and 4 (14.2%) patients received fibrinolytic therapy. 8 (28%) patients required cardiac resuscitation during hospitalization, and 6 people (21.4%) died. In 3 (75%), initially receiving fibrinolytic therapy, fibrinolysis was successful. Stent thrombosis occurred in 8 (34.7%) patients after PCI. Conclusion. We analyzed a series of COVID-19 infections in patients with MI. Found a high incidence of stent thrombosis, which indicates a possible need to adapt the treatment of MI in patients with COVID-19.

Keywords:myocardial infarction, COVID 19, stent thrombosis, percutaneous coronary intervention