Current state and prospects for treatment of colorectal tumors when extraction of samples from natural housings (N.O.S.E.S.)

Cao Yu, Zhang Xinliang, Fu Yu

Colorectal cancer (CRC) is one of the most common malignant tumors of the digestive tract. Recently, there has been an increase in overall morbidity and mortality from CRC, while surgery remains the most effective treatment for CRC. Thanks to the constant modernization of surgical and diagnostic technologies, the constantly improving minimally invasive surgical technique has become one of the standards in the treatment of colorectal cancer. As much attention is paid to the patient's quality of life after surgery as to the oncological and surgical outcome. Thus, both endoscopic transluminal surgery (N.O.T.S.E.) and natural orifice surgery (N.O.S.E.S.) are widely used today, essentially displacing open methods of treatment. In this work, we consider the main methods and historical aspects of the development of N.O.S.E.S. in the treatment of colorectal tumors. It was revealed that N.O.S.E.S. in the treatment of colorectal tumors requires improved extraction methods to prevent local recurrence and infectious complications, for the purpose of which it is necessary to use high-precision endoscopic auxiliary instruments, robotic surgery, and to improve sterilization and washing protocols of the extraction pathways.

Keywords:N.O.S.E.S., N.O.T.S.E., colorectal cancer, laparoscopic surgery, malignant tumors