Study of fat autografts survival affected by mesenchymal stem cells: relevance, efficiency, oncological alertness

Dashtoyan Georgy Eduardovich, Startseva Olesya Igorevna

The article presents a literature review on experimental studies of the angiogenic properties of adipose tissue-derived stem cells and stromal vascular fraction. This study specifically addresses the issue of oncological alertness while using mesenchymal stem cells for the enrichment of adipose tissue. The authors of this study researched the survival rate of fat autografts in animals. The results of an experimental study are presented, according to which the enrichment of transplanted adipose tissue with mesenchymal stem cells improves the lipofilling procedure, stipulates the survival of fat grafts by means of increasing neovascularization as well as reduces the phenomena of fat grafts resorption and fibrosis.

Keywords:adipose tissue stem cells, cancer alertness, cellular stimulation, mesenchymal stem cells, fat grafts, lipofilling, plastic surgery.