Sivets Natallia (Researcher of Laboratory of influenza and influenza-like diseases, applicant for the degree of candidate of biological sciences, Republican Research and Practical Center for Epidemiology and Microbiology, Minsk, Republic of Belarus)
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The study determined the nucleotide sequences of the complete genomes of HBoV1 circulating in our country. Sequence homology of Belarusian bocaparvoviruses with reverence strain ST2 (NC_007455.1) for BLR/Minsk/10/14, BLR/Minsk/11/14 and BLR/Mogilev/241/14 was 99.7%, for BLR/Gomel/ 285/15 was 99.8%. The presence of two unique substitutions P157S and D639K in the regions of the DNA-binding and helicase domains, which can affect the rate of replication and transcription of the respiratory bocaparvovirus.
Keywords:HBoV1, DNA, sequence reaction, genome, amino acid substitutions.
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Citation link: Sivets N. Molecular genetic studies of human bocaparvovirus in children with respiratory infection in the Republic of Belarus // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2022. -№09. -С. 61-64 DOI 10.37882/2223-2966.2022.09.32 |
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