Antiarrhythmic therapy effectiveness evaluation in patient with atrial fibrillation and high ventricular rate before hospitalization

Polyakov Igor Alexeevich, Zinatullina Dilara Sabirovna, Alkova Diana Pavlovna, Vorontsova Marina Konstantinovna

The purpose of this work was to evaluate the antiarrhythmic therapy effectiveness in paroxysmal atrial fibrillation (AF) in elderly patients before hospitalization. A retrospective content analysis of call maps was performed in 224 patients with paroxysmal AF who were treated with a rhythm control strategy. Patients older than 60 years (n=171) constituted group 1 of the study, and group 2 included patients younger than this age (n=53). The assessment of the functional status of the cardiovascular system and the state of the hemodynamic and after the treatment was carried out by measuring blood pressure, electrocardiography. The effectiveness of amiodarone before hospitalization in paroxysmal AF in the elderly has been investigated. Administration of potassium and magnesium aspartate preparations in combination with amiodarone has not been shown to be effective. To achieve the maximum effect, patients over 60 years of age are recommended to administer the maximum dose of amiodarone (450 mg). All patients in this age group are recommended for immediate hospitalization.

Keywords:atrial fibrillation, rhythm control, antiarrhythmic therapy, amiadarone, elderly people.