Tumor of the adrenal medulla (chromaffinoma) is a complex clinical case

Zhilina Anna Nikolaevna, Melnikova Yulia Evgenievna, Chizhova Yulia Anatolyevna, Ignashova Elena Vitalievna, Malygin Alexander Yuryevich

Chromaffinoma (pheochromocytoma) is a tumor of chromaffin cells of the adrenal medulla that produces catecholamines (adrenaline and norepinephrine). The frequency of occurrence of this pathology is approximately 2-8 cases per 1 million population per year [1]. Despite the large number of guidelines and recommendations devoted to the diagnosis and treatment of chromaffinoma, the versatility of the clinical picture of this disease, the low frequency of occurrence in the population causes numerous errors leading to untimely, incorrect treatment of such patients, which increases the risk of complications, reduces the quality of life of patients and ultimately increases the cost of therapy. It should be noted that tumors secreting catecholamines do not always remain detected in a timely manner, which cannot but lead to cardiovascular complications up to a fatal outcome. In this regard, I would like to share my own experience in the management of a patient with chromaffinoma, the rarity of which also lies in the fact that the pathological process is localized in the left adrenal gland, while in 90% of cases pheochromocytoma is localized on the right.

Keywords:chromaffinoma, free metanephrines and normetanephrines, tumor secreting catecholamines, high degree of arterial hypertension