Stable angina in patients with bordeline coronary artery stenosis of high biological age. Residual cardiovascular risk

Yakhontov Davyd A., Ostanina Yuliya Olegovna

Coronary Artery Disease (CAD) remains the main cause of disability and mortality of working age people. Significant part of the stable angina patients (pts) are pts with borderline coronary arteries stenosis (40-70%). A distinctive feature CAD as well as atherosclerotic diseases in general is increased vascular wall stiffness. This is often accompanied by an increase biological (vascular) age of patients (pts). Aim. To study cardiovascular risk factors, angiographic picture and residual cardiovascular risk components in stable angina pts with borderline coronary arteries stenosis of high biological age. Material and methods. 21 stable angina class 1-3 pts (19 men) age 33-66 with borderline coronary arteries stenosis of high biological age based on the coefficient “passport age/biological age” > 1,0 were examined. Results. Pts with stable angina and borderline coronary arteries stenosis of high biological age have a number of unfavorable features that can affect the further course and outcome of the disease. Despite the outpatient treatment the frequency of lipid and inflammatory components of residual risk was found to be high as well as parameters reflecting blood pressure and glycemia insufficient control.

Keywords:Coronary artery disease, borderline coronary artery stenosis, biological age, residual cardiovascular risk