Genetic aspects of SARS-CoV‑2 in the context of influence of the virus on the course of pregnancy and birth

Stefanyan Natella Amletovna, Khashaeva Tamara Hadzhi-Muradovna, Abusueva Zukhra Abusuevna, Mamaeva Salidat Magdievna, Medzhidova Aishat Medzhidovna, Zakarigaeva Raziyat Magomedeminovna

Everyone knows that the world is escalated by viruses due to two fundamental properties inherent in them: the speed of replication and the high level of mutagenicity. At the same time, viruses achieve their goal through the ultimate simplification of their own mechanisms of life and their own structure, however, with their own unique characteristics. This can be understood at least from a comparison of the human genome and the SARS-CoV-2 genome, which actively entered into interspecies struggle in 2020: 3 billion base pairs against 29 thousand. The meaning of the existence of viruses is the maximum capture of target cells and the synthesis of the maximum possible amount viral particles, which, in turn, will continue to infect the living. This article describes in detail the pathomorphological and genomic structure of SARS-CoV-2, its standard and alternative ways of entering the cell, as well as the impact of the virus on the course of pregnancy and childbirth.

Keywords:COVID-19, SARS-CoV-2, coronovirus infection, genome.