Effect of polysaccharide of calendula flowers on blood and hemorous

Sirotkina D. S., Sychev I. A., Cherdantseva T. M., Kolosova T. Yu.

A study was carried out to study the effect of calendula polysaccharide on the blood and hematopoiesis processes in healthy animals. A polysaccharide was isolated from the air-dry pharmaceutical raw material of calendula flowers, its qualitative and quantitative monosaccharide composition was determined. The effect of the polysaccharide on the blood of healthy animals was studied in Wistar rats. In the blood of experimental and control animals, the number of erythrocytes and hemoglobin, the total number of leukocytes and lymphocytes was determined. At the same time of the experiment, the number of erythroblastic islets of bone marrow isolated from the femur bones of control and experimental animals was determined. The data obtained indicate that the polysaccharide of calendula flowers stimulates the processes of hematopoiesis, increasing the total number of erythroblastic islets in the bone marrow of experimental rats. The polysaccharide drug increases the number of red blood cells and hemoglobin levels, increases the number of lymphocytes and monocytes, and reduces the total number of leukocytes.

Keywords:polysaccharide of calendula flowers, erythroblastic islets, bone marrow, erythrocytes, hemoglobin, lymphocytes, leukocytes, monocytes.