Phytochemical study and practical significance of some species of the genus (cephalaria schrad). from the family (dipsacaceae lindl.) growing in the flora of Azerbaijan

Aleskerova Adelya Novruz, Rasulov Faig Ali, Jahangirova Ilhama Rafig, Guliyeva Aishen Farman, Mustafayeva Immi-Gulsum Abdulali

The family Dispacaceae includes 9 genera and about 250 species. In Azerbaijan, 5 genera are represented with approximately 30 species. The species of this family have valuable pharmacological properties and have long been used in folk medicine in the treatment of various diseases. The article presents the results of studying the phytochemical composition of aboveground and underground organs, the essential oil of flowers, and the fumigant activity of species of the genus Cephalaria Schrad. In the sum of saponins obtained from the roots and aerial parts of both species, cephalaroside A and cephalaroside C were isolated. Based on the results of UV, 1H, 13C NMR and mass spectra, comparison of physicochemical constants with literature data, chemical (acid and alkaline hydrolysis, acetylation, methylation) transformations obtaining flavonoids were identified with apigenin, hyperoside, quercimerythrin, cynaroside and polustroside. It was found that the dominant components of the essential oil of C. gigantea are 1,8 - cineole and α - thujone. The deterrent effect of the essential oil of C. gigantea was established, which lasted for 5-6 hours. Because of this, C. gigantea essential oil has been recommended for use as a repellant.

Keywords:Cephalaria Schrad., chemical composition, fumigant action.