Menopausal metabolic syndrome. Ways to prevent complications

Urudzheva Naida Ganifaevna, Esedova Asiyat Esedovna, Mammadov Ferzi Sultanovich

Menopause is characterized by symptoms such as hot flashes, insomnia, mood disorders, sexual dysfunction, weight gain and cognitive decline. Estradiol is involved in the processes of homeostasis, in the regulation of utilization and conservation of energy, so its deficiency gradually leads to the development of menopausal metabolic syndrome, which is accompanied by the development of insulin resistance, increased coagulation potential, obesity. In Russia, the prevalence of MS ranges from 20 to 35%, and in women it occurs 2.5 times more often and the number of patients increases with age. MS in postmenopausal women is observed in 40% of cases. Obesity increases the risk of developing many malignant processes, including breast, colon, pancreatic, bladder and endometrial cancers. Arterial events occurring in postmenopausal patients include myocardial infarction, ischemic stroke, hemorrhagic stroke and peripheral arterial events that are associated with dyslipidemia, diabetes, hypertension, obesity, increased coagulation. The main goal in the treatment of MS is non-drug measures that are aimed at reducing body weight, giving up bad habits, it is possible to prescribe menopausal hormone therapy (MGT).

Keywords:menopause, metabolic syndrome, menopausal hormone therapy, obesity, arterial hypertension, hypercoagulation, modified menopausal index, risk of arterial events.