Possibilities of verifying the etiology of exudative pleurisy based on multivariate mathematical modeling

Smirnova Natalia Yurievna, Trishin E. V., Shubin L. B.

This work analyzes a specific set of clinical data collected from a group of patients suffering from pleural effusions of various etiologies. The aim of the work is to develop profiles of patients with exudative pleuritis. Exudative pleuritis is a complication of other pathologies, most often of an inflammatory nature, resulting in the accumulation of fluid in the pleural cavity. In our study, we identified three study groups: nonspecific parapneumonic pleuritis, tuberculous and metastatic pleuritis. In total, we analyzed 352 cases of exudative pleuritis, and 20 cases of the disease with pneumonia caused by coronavirus infection. To analyze these three groups for a number of selected features, we used the methods of mathematical statistics. A set of variables corresponding to the characteristics of each of the three groups was identified. These characteristics are significantly different and form the profile of the patient with exudative pleuritis.

Keywords:exudative pleuritis, exudate, metastatic pleurisy, differential diagnosis, videothoracoscopy.