MAIN DIRECTIONS OF PHARMACOPROPHYLAXIS OF ACUTE POSTOPERATIVE PANCREATITIS THROUGH PREVENTION OF ACTIVATION OF INFLAMMATORY

Pliev Soslan Alanovich, Khutiev Tsara Sardionovich, Beslekoev Uruzmag Solomonovich

Acute postoperative pancreatitis (API) as a complication of surgical interventions and endoscopic retrograde cholangiopancreatography is a dangerous condition that requires attention in relation to its prevention. When carrying out preventive measures for this complication, special attention is paid to preventing the activation of the inflammatory cascade, one of the first reactions that occurs at API. The paper analyzes the main areas of research carried out in relation to the pharmacoprophylaxis of the development of inflammation at API. It has been shown that, along with the traditionally used indomethacin, the possibilities of using other non-steroidal anti-inflammatory drugs are being actively studied.

Keywords:acute postoperative pancreatitis, endoscopic retrograde cholangiopancreatography, pharmacoprophylaxis, prevention of inflammatory cascade activation, non-steroidal anti-inflammatory drugs