COMPARATIVE ANALYSIS OF THE EFFECT IN THE TREATMENT OF VARIOUS TYPES OF OSTEOARTHRITIS OF THE KNEE JOINT WITH HYALURONIC ACID IN COMBINATION WITH PLATELET-RICH PLASMA

Belov Alexander Nikolaevich, Belova Olga Anatolievna, Belova Elizaveta Alexandrovna, Biskaev Pavel Olegovich

In the last decade in medicine, there has been a significant increase in interest in the treatment of osteoarthritis of large joints with the help of platelet-rich plasma (Platelet Rich Plasma - hereinafter referred to as PRP). This is due to its effectiveness with absolute safety. rather low cost and lack of dependence on the supplies of pharmaceutical companies. This biotechnological method has been used in dentistry, ophthalmology, cosmetology, cardiology, combustiology for about 30 years. In the last decade, traumatologists and orthopedists have begun to actively use PRP for the treatment of injuries of muscles, tendons, ligaments, and osteoarthritis. We proposed to combine platelet-rich plasma with hyaluronic acid for intra-articular injections in osteoarthritis of the knee, taking into account special rheological properties of glycosaminoglycan, allowing the formation of a matrix with pronounced viscoelastic properties.

Keywords:platelet-rich plasma, hyaluronic acid, regeneration, traumatology, orthopedics, osteoarthritis, knee joint