ISCHEMIC HEART DISEASE IN THE POST-COVID PERIOD (LITERATURE REVIEW)

Derisheva Daria A., Yahontov Davyd

Coronavirus disease is recognized as a multisystem disease. Infection with the SARS-CoV-2 virus induce host immune responses that can have systemic effects through activation of inflammatory pathways, hypercoagulability, endothelial cell dysfunction, and thromboembolism with potential target organ damage, including cardiovascular system. From the first days of pandemic, it was clear that SARS-CoV-2 in acute phase can damage the heart and blood vessels. While acute COVID-19 infection has been associated with new onset coronary artery disease, long-term outcomes (up to one year of coronary artery disease infection) have not been fully studied and analyzed. In addition, how the virus causes long-term damage to the heart and blood vessels remains a subject of debate and active research. Presented literature review reflects the current state of practical directions in study of COVID-19 impact on the development of cardiovascular diseases in long term in general and in coronary artery disease in particular.

Keywords:ischemic heart disease, Infection SARS-CoV-2 coronavirus disease, post-COVID period, COVID-19, cardiovascular complications