THE ROLE OF CORRECTION OF INTESTINAL MICROBIOME DISORDERS IN AN INTEGRATED APPROACH TO THE TREATMENT OF SARCOPENIA IN THE ELDERLY: A NARRATIVE MINI-REVIEW

Ushakov Maxim Aleksandrovich

The issue of sarcopenia, manifested by a reduction in strength, mass, and function of skeletal muscles, is becoming increasingly relevant due to the aging population in Russia. This study explores the potential correlation between changes in the composition and metabolism of the gut microbiota and the development of age-related sarcopenia. Primary focus is given to the prospects of adjusting the gut microbiota as an approach to the prevention and treatment of sarcopenia in the elderly, given that existing therapeutic methods are imperfect. Contemporary literature data was used for analysis. The results suggest that an imbalance in the gut microbiota may play a significant role in the onset of sarcopenia, and its correction could become a potential component of treatment. However, further research in this field is required to draw definitive conclusions

Keywords:sarcopenia; elderly; microbiota; treatment; pathogenesis