CYTOTOXIC EFFECT OF PHLOJODICARPUS SIBIRICUS ON CANCER HEPG2 AND HELA LINES

Egorov Andrei Nikolaevich, Golderova Aitalina Semenovna, Troev Ivan Petrovich, Nikolaeva Irina Eduardovna, Gotovtsev Radomir Andreevich

Despite the many synthetic substances used in modern pharmacology, the issue of finding new substances that would be safe and effective is as pressing as before. Plants growing in a sharply continental climate are promising and poorly studied. At this time, the Phlojodicarpus sibiricus is a promising, but poorly studied medicinal plant, growing in cryolithozone conditions it can be a source of biologically active compounds with oncoprotective and antitumor activity. The aim of this study was to evaluate the cytotoxic effect of Phlojodicarpus sibiricus lyophilisate on the proliferative activity of cultured cancer cells on HepG2 and HeLa.

Keywords:Phlojodicarpus sibiricus, lyophilisate, HepG2, HeLa, cytotoxicity, MTT test.