METHOD FOR PREDICTING THE RISK OF DEVELOPMENT OF MALIGNANT NEW TUMORS OF THE LUNG

Malashenko Viktor Nikolaevich, Vorobiev Tikhon Yurievich, Goncharova Natalya Vladislavovna

The work was carried out on the basis of statistical data processing by creating a multifactor model. In the process of developing the method, a survey was conducted on 559 people (304 people (54.38%) - positive group: 1 - there are malignant tumors of the lungs; 255 people (45.62%) - negative group: 0 - no malignant tumors of the lungs), on on the basis of which a questionnaire of 75 questions was formed. These questions are compiled on the basis of genetic and modifying – exogenous and endogenous risk factors for the development of tumor and pre-tumor lung diseases, early clinical signs and general questions. In addition, the work used materials from the medical histories of the patients surveyed and data from histological studies. The data were processed using a statistical software package: STATISTICAStatSoft, Inc. (2014) (dataanalysissoftwaresystem), version 12.5, and MedCalcStatisticalSoftwareversion 15.8 (MedCalcSoftwarebvba, Ostend, Belgium; 2015) in the Windows environment, and multivariate statistical analysis was also applied.

Keywords:Lung cancer; questionnaire screening; risk factors; at-risk groups; multivariate statistical ROC analysis