MAYER-ROKITANSKY-KUSTNER-HAUSER SYNDROME: WAYS TO OVERCOMING INFERTILITY AND IMPLEMENTING REPRODUCTIVE FUNCTION (CLINICAL CASE)

Rossolko Dmitry S., Chi Hee Won, Korolevskaya Angelina V., Makolkin Alexander A.

It has been determined that Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) is a disorder of the intrauterine development of the Müllerian ducts, leading to aplasia of the vagina and uterus. It is noted that the syndrome is diagnosed in 2 patients out of 10000 and accounts for 5–10% of all developmental defects. The types of MRKH are described. It was revealed that MRKH syndrome has a direct effect on the reproductive function of the female body, which is associated with absolute infertility due to the uterine factor. It is noted that the only option for motherhood for patients with MRKH is surrogacy. A rare clinical case of overcoming infertility in MRKH syndrome with the help of modern high reproductive technologies is described. Taking into account the optimal chosen tactics for managing the patient, a favorable outcome for the woman was obtained. It was concluded that laparoscopic puncture of ovarian follicles shows excellent results in overcoming infertility and realizing reproductive function.

Keywords:Mayer-Rokitansky-Küstner-Hauser syndrome, uterine aplasia, uterine developmental abnormalities, infertility, assisted reproductive technologies (ART).