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USE OF PLATELET RICH PLASMA IN ONCOPLASTIC BREAST RECONSTRUCTION: A REVIEW OF THE CURRENT STATE AND PROSPECTS

Khorobrykh Tatiana Vitalevna  (doctor of medical sciences Professor of the Russian Academy of Sciences, Head of the Department of Faculty Surgery No. 2 named after G.I. Lukomsky of the I.M. Sechenov First Moscow State Medical University Director of the Clinic of Faculty Surgery No. 2 of the University Clinical Hospital No. 4 of the I.M. Sechenov First Moscow State Medical University Head of the Department of Faculty Surgery No. 2 of the I.M. Sechenov First Moscow State Medical University )

Baranova Madina Petrovna  (candidate of medical sciences, Assistant Professor of the Department of Faculty Surgery No.2 named after G.I. Lukomsky, I.M. Sechenov First Moscow State Medical University Head of the Surgical Department of Breast and Skin Tumors of the Faculty Surgery Clinic No. 2 of the University Clinical Hospital No. 4 of the I.M. Sechenov First Moscow State Medical University Assistant of the Department of Faculty Surgery No. 2 named after G.I. Lukomsky of the I.M. Sechenov First Moscow State Medical University )

Wang Shuowen   (Postgraduate student of the Department of Faculty Surgery No. 2 named after G.I. Lukomsky of the I.M. Sechenov First Moscow State Medical University Surgical Department of Breast and Skin Tumors of the Faculty Surgery Clinic No. 2 of the University Clinical Hospital No. 4 of the I.M. Sechenov First Moscow State Medical University )

He Mingze   (Postgraduate student at the Institute of Urology and Human Reproductive Health of the I.M. Sechenov First Moscow State Medical University Department of Urology No.2 R.M. Fronstein Urology Clinic of the University Clinical Hospital No. 2 of the I.M. Sechenov First Moscow State Medical University )

Gorbunov Andrey Sergeevich  (candidate of medical sciences Associate Professor of the Department of Faculty Surgery No. 1 named after N.N. Burdenko of the First Sechenov Moscow State Medical University Surgeon of the highest category - Surgical Department of the N.N. Burdenko Faculty Surgery Clinic University Clinical Hospital No. 1 of the I.M. Sechenov First Moscow State Medical University )

Kulaga Andrey Vladimirovich  (candidate of medical sciences Assistant Professor of the Department of Faculty Surgery No. 2 named after G.I. Lukomsky, I.M. Sechenov First Moscow State Medical University Oncologist, mammologist, surgeon, oncologist. - Surgical Department of Breast and Skin Tumors of the Faculty Surgery Clinic No. 2 of the University Clinical Hospital No. 4 of the I.M. Sechenov First Moscow State Medical University )

Breast cancer is the most commonly diagnosed cancer and the second leading cause of death among women. Surgery remains the main method of treating breast cancer as part of complex therapy. On the other hand, this treatment method is accompanied by physical discomfort and psychological trauma. Fat grafting with autologous fat is a promising alternative treatment for scar deformities and soft tissue defects after destructive or conservative breast cancer surgery. It is easily accessible and ensures equal aesthetic growth of donor and recipient sites. However, there are concerns about unpredictable survival and fat retention after grafting. Regenerative therapy using platelet-rich plasma for fat transfer is a modern solution to optimize this problem. Platelet-rich plasma, derived from autologous plasma, is fully biocompatible, non-immunogenic and provides a large number of different growth factors for soft tissue regeneration and wound healing.

Keywords:Platelet-rich plasma, autologous fat transfer, breast reconstruction, breast cancer, fat grafting.

 

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Citation link:
Khorobrykh T. V., Baranova M. P., Wang S. , He M. , Gorbunov A. S., Kulaga A. V. USE OF PLATELET RICH PLASMA IN ONCOPLASTIC BREAST RECONSTRUCTION: A REVIEW OF THE CURRENT STATE AND PROSPECTS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№06/2. -С. 216-223 DOI 10.37882/2223-2966.2024.6-2.39
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