SURGICAL RESULTS OF TREATMENT OF PATIENTS WITH COLORECTAL CANCER

Kaganov Oleg I., Frolov Sergey A., Kozlov Alexey M., Shvets Denis S., Blinov Nikita V.

In recent years colorectal cancer is taking leading positions in the structure of cancer mortality in Samara Region. Annually more than a thousand surgical interventions are performed for patients with colorectal cancer in high-volume medical centers. The analysis of 5 years surgical treatment results for patients with colorectal cancer who were treated in the department of abdominal oncology of Samara Regional Clinical Oncology Dispensary was performed. The study was prospective, the structure of complications and significance of various prognostic factors were studied. The frequency of postoperative complications was 23%, but the proportion of clinically significant complications Clavien-Dindo Grade≥III did not exceed 9%. The mortality rate was 1%. Significant risk factors for the development of septic complications in patients with colorectal cancer care: male gender, obesity, low rectal cancer, neoadjuvant chemoradiotherapy, malnutrition. A thorough assessment of perioperative risks, predicting the development of postoperative complications, can improve the efficiency of the use medical clinic resources, reduce mortality rate and the number of undesirable events, especially in the group of high-risk patients. COVID-19 is also a significant prognostic factor for postoperative inflammatory complications in patients with colorectal cancer.

Keywords:colorectal cancer, postoperative complications, prognostic factors, COVID-19.