THE EFFECT OF POLYPHENOLIC CONCENTRATES ON REHABILITATION IN RHEUMATOID ARTHRITIS

Pastushenko Alina Eduardovna, Velikaya Anastasiya Vladislavovna, Bykovskiy Ilya Valerevich, Ametova Lilya Osmanovna, Rutchkin Ioann Aleksandrovich

Rheumatoid arthritis (RA) is a common chronic inflammatory joint disease that affects approximately 1% of the world's population. It is characterized by chronic inflammation, leading to joint destruction, pain, movement limitations and disability. There are many treatments for RA, including pharmacotherapy, physiotherapy, surgery, and rehabilitation. However, some methods have side effects and limitations in long-term use. The potential anti-inflammatory and antiarthritic effects of polyphenols, biologically active compounds from plant products, are being investigated. Polyphenols are known for their antioxidant, anti-inflammatory and immunomodulatory properties, which can positively affect the symptoms of RA.

Keywords:rheumatoid arthritis, polyphenols, inflammation, autoimmunity