SINGLE-FACTOR PREDICTION OF RISKS OF DEVELOPMENT AND PROGRESSION OF CARDIOVASCULAR SYSTEM DISEASES

Derbeneva Svetlana Anatolevna

The purpose of the study is to study clinical, instrumental and laboratory parameters as markers of the development and progression of diseases of the cardiovascular system. As a result of a survey of 956 patients with diseases of the cardiovascular system, specific factors for predicting the development of coronary artery disease were identified: silent myocardial ischemia, post-infarction cardiosclerosis, conditions after surgical treatment, angina pectoris class I. Prediction of the risk of developing a particular clinical event from specific quantitative or binary indicators of the metabolic status of patients was carried out using the Pearson Chi-square test. In one clinical case of IHD, the key biomarkers were identified as metabolic status, in another case the parameters of the clinical course of atherosclerotic disease, in the third and fourth – their combination. Taking into account the presence of these factors, it is possible to carry out measures for their adequate and timely correction, thereby preventing the development and progression of these nosological forms.

Keywords:diseases of the cardiovascular system, prognosis, coronary heart disease, risk factors