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INTRAOPERATIVE RADIOTHERAPY IN THE TREATMENT OF PANCREATIC CANCER

Abdulaeva R. Sh.  (predoctoral fellow of the Chemotherapy Department №2 of N.N.Trapeznikov Research Institute of Clinical oncology of Federal State Budgetary Institution «N.N. Blokhin National Medical Research Center of Oncology» оf the Ministry of Health of the Russian Federation )

Makiev G. G.  (oncologist of the Chemotherapy Department №2 of N.N.Trapeznikov Research Institute of Clinical oncology of Federal State Budgetary Institution «N.N. Blokhin National Medical Research Center of Oncology» оf the Ministry of Health of the Russian Federation )

Mezhekova D. Y.  (resident of the Department of Oncology and Radiation Therapy, Federal State Autonomous Educational Institution of Higher Education «N.I. Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation)

Chikhareva Y. E.  (oncologist of the Chemotherapy Department №2 of N.N.Trapeznikov Research Institute of Clinical oncology of Federal State Budgetary Institution «N.N. Blokhin National Medical Research Center of Oncology» оf the Ministry of Health of the Russian Federation )

Dinaeva E. A.  (oncologist of the Chemotherapy Department №2 of N.N.Trapeznikov Research Institute of Clinical oncology of Federal State Budgetary Institution «N.N. Blokhin National Medical Research Center of Oncology» оf the Ministry of Health of the Russian Federation )

Bazin I. S.  (leading researcher of the Chemotherapy Department №2 of N.N.Trapeznikov Research Institute of Clinical oncology of Federal State Budgetary Institution «N.N. Blokhin National Medical Research Center of Oncology» оf the Ministry of Health of the Russian Federation )

The rather modest results of pancreatic cancer treatment indicate the need to study ways to improve survival rates in this category of patients. The place of radiotherapy in the treatment of localised pancreatic cancer, in particular intraoperative radiotherapy (IORT), is interesting and understudied. This review presents current data on the value of intraoperative radiotherapy and its place in the treatment of localised pancreatic cancer. IOLT in comparison with other types of radiotherapy is characterised by a lower number of complications. Intraoperative radiotherapy significantly improves locoregional control of the disease, but the data on survival are controversial and require further investigation.

Keywords:pancreatic cancer, intraoperative radiotherapy, neoadjuvant radiotherapy, chemotherapy, resectable and borderline resectable cancer, locally advanced cancer.

 

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Citation link:
Abdulaeva R. S., Makiev G. G., Mezhekova D. Y., Chikhareva Y. E., Dinaeva E. A., Bazin I. S. INTRAOPERATIVE RADIOTHERAPY IN THE TREATMENT OF PANCREATIC CANCER // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№08. -С. 158-162 DOI 10.37882/2223-2966.2024.8.01
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