Kench Ulash Salimovich (Postgraduate student
V.A. Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences
)
Sologova Susanna Sergeevna (PhD, Associate Professor, Department of Pharmacology
I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
)
Prasolov Vladimir Sergeevich (Dr. Biological Sciences, Corresponding Member of the Russian Academy of Sciences, Leading Researcher
V.A. Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences
)
Spirin Pavel Vladimirovich (PhD, Senior Researcher
V.A. Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences
)
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This review presents an analysis of the current state of the problem, devoted to the study of the role of autophagy in the development of various pathological conditions. As part of the preparation of this review article, a deep analysis of modern scientific literature covering this issue was carried out. A special place is occupied by sections describing the mechanism of action of various autophagy modulators in the context of their use to combat various diseases. This review is of significant interest both to researchers who study fundamental issues related to the development of various diseases, and to those involved in the development and implementation of drugs in clinical practice.
Keywords:autophagy, inhibitors, activators, lysosomes, cell death, therapeutic agents.
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Read the full article …
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Citation link:
Kench U. S., Sologova S. S., Prasolov V. S., Spirin P. V. AUTOPHAGY AND WAYS OF ITS REGULATION WITH THE HELP OF PHARMACOLOGICAL DRUGS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2024. -№10. -С. 26-36 DOI 10.37882/2223-2966.2024.10.24 |
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