Polidanov Maxim Andreevich (research department specialist, assistant of the Department of Biomedical Disciplines, University «Reaviz», Saint Petersburg, Russian Federation)
Kapralov Sergey Vladimirovich (Doctor of Medicine Sciences, associate professor, Head of the Department of Faculty Surgery and Oncology, Saratov State Medical University named after V.I. Razumovsky)
Volkov Kirill Andreevich (Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation)
Petrunkin Rodion Pavlovich (Private University «Reaviz», Saint Petersburg, Russia)
Danilov Andrey Dmitriyevich (Assistant of the Department of Faculty Surgery and Oncology, Saratov State Medical University named after V.I. Razumovsky)
Yuanov Aslan Askerbievich (Doctor of Medical Sciences, Professor of the Department of Surgery and Oncology, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russian Federation)
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The aim of the study is to develop a method that is closest to the clinical course of pelvic abscess, which is a delimited accumulation of pus in the rectovaginal cavity. Materials and Methods. A series of experiments on 20 female laboratory rats of “standard” breed weighing 200±50 g were carried out in the operative unit of the Department of Faculty Surgery and Oncology of V.I. Razumovsky Saratov State Medical University. Results of the study. It was proved that pelvic abscess is modeled within 5 days from the experiment in 100% of animals and has expressed morphological (macro- and microscopic) signs confirmed by microbiological data. Conclusions. The developed method is low-traumatic, provides guaranteed formation of pelvic abscess and does not require any complex manipulations and high technical equipment, provides the term of abscess formation up to 5 days.
Keywords:Pelvic abscess, Douglas abscess, experimental modeling, female rats.
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Citation link:
Polidanov M. A., Kapralov S. V., Volkov K. A., Petrunkin R. P., Danilov A. D., Yuanov A. A. EXPERIMENTAL SUBSTANTIATION OF THE METHOD OF MODELING PELVIC ABSCESS ON FEMALE RATS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2025. -№01/2. -С. 120-123 DOI 10.37882/2223-2966.2025.01-2.16 |
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